Researchers are confirming “drug holidays” require closer follow-up and attention, especially in patients at high risk of fracturing. Patients who take osteoporosis drugs for years at a time are typically advised to take a “drug holiday” or temporarily discontinue taking the drugs to minimize the likelihood of dangerous side effects. These side effects generally target the jaw and thighs, having been linked to osteonecrosis of the jaw and atypical femur fracture.
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